Learning health systems and the future of clinical research

Jordan C Apfeld1, Katherine J Deans1

  • 1Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, OH; Center for Innovation in Pediatric Practice, Nationwide Children's Hospital, Columbus, OH; Department of Surgery, Division of Pediatric Surgery, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, OH.

Insights

Pediatric surgeons prioritize children's health needs, driving clinical care and scientific discovery. Future research will focus on patient-centric approaches within evolving healthcare systems.

Area of Science:

  • Pediatric Surgery
  • Clinical Research
  • Healthcare Systems

Background:

  • Pediatric surgeons exhibit a strong commitment to children's healthcare.
  • This dedication influences both clinical practice and scientific advancement in the field.

Purpose of the Study:

  • To outline the future of pragmatic clinical research in pediatric surgery.
  • To emphasize the integration of patient-centric principles in research design.

Main Methods:

  • The article discusses the evolution of clinical research methodologies.
  • It highlights the importance of understanding patient needs and expectations.

Main Results:

  • Future clinical research will be patient-centric.
  • Research will be embedded within the learning health system framework.

Conclusions:

  • The future of pediatric surgical research is patient-centric.
  • Pragmatic clinical research designs will be crucial in evolving healthcare systems.

Related Concept Videos

Health Information Technology and Healthcare Information System01:30

Health Information Technology and Healthcare Information System

Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
3.2K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
6.1K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.1K
Nursing Clinical Information System01:27

Nursing Clinical Information System

Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
1.2K
Current Trends in Nursing II01:30

Current Trends in Nursing II

Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...
3.3K
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.5K