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Evaluating Outcomes in Adolescents With Pilonidal Disease Treated With Pilonidal Sinus Trephination
Katherine C Bergus1, Carley Lutz1, Josh Bricker1
1Center for Surgical Outcomes Research and Department of Pediatric Surgery, Nationwide Children's Hospital, Columbus, Ohio.
The Journal of Surgical Research
|May 16, 2025
Summary
Pilonidal sinus trephination is a viable option for adolescents with chronic disease, though healing and recurrence rates vary. Non-White race was associated with delayed healing and higher recurrence in this study.
Area of Science:
- Pediatric Surgery
- Dermatology
- Infectious Disease
Background:
- Pilonidal disease is a chronic infection affecting the gluteal cleft.
- Trephination is a known treatment, but adolescent outcomes are understudied.
- This study evaluates trephination's effectiveness in adolescents.
Purpose of the Study:
- To investigate wound healing after pilonidal sinus trephination in adolescents.
- To assess disease recurrence rates at one year post-trephination.
- To identify predictors of healing and recurrence in this demographic.
Main Methods:
- Retrospective review of 63 patients aged 10-21 years undergoing trephination.
- Data collected on demographics, treatment, and 12-month outcomes.
- Firth penalized logistic regression used to find predictors of healing and recurrence.
Main Results:
- Delayed wound healing occurred in 20.5% of patients.
- One-year recurrence rate was 25.0%.
- Non-White race was associated with delayed healing (OR 7.31) and recurrence (OR 8.85).
Conclusions:
- Pilonidal sinus trephination can be suitable for select adolescents with chronic, fistulous disease.
- Race and ethnicity may influence healing complications and recurrence.
- Further research is needed to confirm these associations.

