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Practical Guidance for Clinical Microbiology Laboratories: A Comprehensive Update on the Problem of Blood Culture
Gary V Doern1, Karen C Carroll2, Daniel J Diekema3
1Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA gdoern@nc.rr.com.
Abstract:
In this review, we present a comprehensive discussion of matters related to the problem of blood culture contamination. Issues addressed include the scope and magnitude of the problem, the bacteria most often recognized as contaminants, the impact of blood culture contamination on clinical microbiology laboratory function, the economic and clinical ramifications of contamination, and, perhaps most importantly, a systematic discussion of solutions to the problem. We conclude by providing a series of unanswered questions that pertain to this important issue.
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