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Updated: Jan 4, 2026

Dechorionation of Medaka Embryos and Cell Transplantation for the Generation of Chimeras
Published on: December 22, 2010
Time to rethink the law on part-human chimeras
Julian J Koplin1,2, Julian Savulescu1,2,3
1Biomedical Ethics Research Group, Murdoch Children's Research Institute, Parkville VIC 3052, Australia.
None:
It may soon be possible to generate human tissues and organs inside of part-human chimeras via a technique known as interspecies blastocyst complementation. Using Australian legislation as a case study, we show why this technique of creating part-human chimeras falls within the gaps of existing legislation. We give an overview of the key ethical issues raised by part-human chimera research, and we describe how well these issues are met by a range of possible regulatory approaches. We ultimately argue that regulation of part-human chimera research should be (re)designed to balance two key aims: to facilitate ethical research involving part-human chimeras and to prevent unethical experimentation with chimeras that have an uncertain-and potentially substantial-degree of moral status.
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