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Stereotactic Radiosurgery for Carcinoid Brain Metastasis: A Case Report
Felicia Cao1, David M Sada2, Syeling Lai3
1Internal Medicine, Medical Scientist Training Program, Baylor College of Medicine, Houston, USA.
Cureus
|November 1, 2019
Summary
Carcinoid brain metastases are rare and have a poor prognosis. This case highlights rectal carcinoid spread to the cerebellum and reviews treatment options, including temozolomide and stereotactic radiosurgery.
Area of Science:
- Neuro-oncology
- Gastroenterology
- Endocrinology
Background:
- Carcinoid tumors, neuroendocrine neoplasms, can rarely metastasize to the brain.
- Brain metastases from carcinoid tumors are associated with poor patient outcomes.
- Treatment strategies for carcinoid brain metastases are not well-established.
Observation:
- A rare case of rectal carcinoid metastasizing to the cerebellum is presented.
- The patient's rectal carcinoid tumor spread to the brain, specifically the cerebellum.
- This highlights the potential for distant metastasis in carcinoid disease.
Findings:
- Review of current chemotherapeutic regimens for carcinoid tumors.
- Evaluation of temozolomide as a potential treatment for carcinoid brain metastases.
- Assessment of stereotactic radiosurgery as a therapeutic option.
Implications:
- Understanding the metastatic potential of carcinoid tumors to the central nervous system.
- Informing treatment decisions for rare carcinoid brain metastases.
- Guiding future research into optimal therapeutic strategies, including novel agents and radiation techniques.
