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Related Experiment Video

Updated: Jan 4, 2026

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Negative pressure wound therapy with instillation: International consensus guidelines update.

Paul J Kim1, Christopher E Attinger2, Thomas Constantine3

  • 1Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.

International Wound Journal
|November 1, 2019
PubMed
Summary

Updated international consensus guidelines for negative pressure wound therapy with instillation and dwell time (NPWTi-d) were developed. These guidelines refine best practices for using NPWTi-d, considering complex wounds and patient conditions.

Keywords:
NPWTitopical wound solutionwound bioburdenwound cleansing, V.A.C. Veraflo therapy

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Area of Science:

  • Wound Care
  • Medical Technology
  • Clinical Practice Guidelines

Background:

  • Negative pressure wound therapy with instillation and dwell time (NPWTi-d) use is increasing due to complex wounds.
  • Existing NPWTi-d guidelines are over six years old, necessitating an update.
  • Growing evidence and global experience highlight the need for revised best practices.

Purpose of the Study:

  • To develop updated international consensus guidelines for NPWTi-d best practices.
  • To refine recommendations for NPWTi-d application settings, topical solutions, and patient/wound selection.
  • To address various dressing and setting configurations for NPWTi-d.

Main Methods:

  • An international, multidisciplinary expert panel convened in February 2019.
  • Recommendations were based on panel expertise and published research.
  • Consensus was achieved through >80% agreement among panellists.

Main Results:

  • Updated best practice recommendations for NPWTi-d were established.
  • Guidelines address appropriate application settings and topical wound solution selection.
  • Specific wound and patient characteristics for NPWTi-d use were refined.

Conclusions:

  • The published guidelines represent a refinement of NPWTi-d parameters.
  • These updated recommendations aim to improve the use of NPWTi-d in complex wound management.
  • The consensus guidelines provide current best practices for clinicians worldwide.