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Room temperature/Corcoran/Dow Corning™-Silicone plastination process.

Dmitry Starchik1, Robert W Henry2

  • 1International Morphological Centre, Saint Petersburg, Russia.

Anatomia, Histologia, Embryologia
|November 1, 2019
PubMed
Summary
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A new room temperature silicone plastination technique offers a stable, non-toxic alternative to the established cold temperature method for preserving biological specimens. This advancement provides similar high-quality results without the need for extreme cold.

Area of Science:

  • Anatomy and Histology
  • Biotechnology and Biomaterials

Background:

  • The cold temperature/S10/von Hagens plastination technique has been the gold standard for preserving biological specimens for two decades.
  • This method produces dry, aesthetically pleasing specimens but requires sub-zero temperatures (-15°C) due to the instability of the polymer-catalyst mixture.

Purpose of the Study:

  • To introduce and describe a novel room temperature silicone plastination technique.
  • To present an alternative preservation method that eliminates the need for cold temperatures and toxic chemical residues.

Main Methods:

  • A new silicone polymer (Cor-tech) and cross-linker were combined to create a stable room temperature impregnation mix.
  • The technique involves impregnating specimens with the silicone mix at room temperature, followed by catalyst application for curing.
Keywords:
degreasingdehydrationfreeze substitutionimpregnationlow molecular weight siliconeplastinateroom temperature plastination

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  • This process mirrors the four basic steps of traditional plastination but differs in the sequence of component combination.

    • Main Results:

    • The room temperature technique yields plastinates comparable in quality and practicality to those produced by the cold method.
    • Specimens preserved using this method are beautiful, dry, and permanently preserved without toxic chemical residues.
    • The silicone impregnation mix is stable at room temperature, simplifying the preservation process.

    Conclusions:

    • The Room temperature/Dow Corning™/Corcoran-Silicone plastination technique provides a viable, stable, and safer alternative to cold temperature plastination.
    • This method offers similar high-quality preservation results, making biological specimens accessible for demonstration and study without hazardous conditions.