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Complementary and Integrative Therapies for Childhood Atopic Dermatitis
Adrienne L Adler-Neal1, Abigail Cline2, Travis Frantz3
1Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA. aadler@wakehealth.edu.
Children (Basel, Switzerland)
|November 2, 2019
Summary
Certain probiotic strains, like L. plantarum and L. fermentum, show promise in improving childhood atopic dermatitis severity. More research is needed to confirm these findings and explore other complementary and integrative medicine (CIM) options.
Area of Science:
- Integrative medicine
- Pediatric dermatology
- Microbiome research
Background:
- Childhood atopic dermatitis (AD) is a chronic skin condition with significant patient and societal costs.
- Current treatments may lead to poor patient satisfaction and require long-term adherence.
- Complementary and integrative medicine (CIM) is of growing interest for managing pediatric AD.
Purpose of the Study:
- To evaluate the efficacy of CIM interventions for childhood atopic dermatitis.
- To synthesize findings from randomized controlled trials (RCTs) on CIM for pediatric AD.
Main Methods:
- A systematic literature review was conducted using PubMed.
- Searched for CIM treatments targeting pediatric atopic dermatitis.
- Extracted data on study design, population, efficacy, and treatment parameters.
Main Results:
- Twenty trials focused on probiotic/prebiotic interventions.
- Three trials examined vitamin supplementation.
- Two trials investigated Chinese herbal medicine.
- Probiotics L. fermentum and L. plantarum demonstrated the most promising results.
Conclusions:
- Specific probiotic strains, L. plantarum and L. fermentum, may reduce clinical severity in pediatric AD.
- Further RCTs are necessary to validate these probiotic effects.
- Additional research is needed to explore other CIM therapies for childhood AD.
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