Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

289
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
289
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

591
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
591
Ultrasonography01:17

Ultrasonography

7.2K
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
7.2K
Ultrasound I: Abdominal Ultrasonography01:20

Ultrasound I: Abdominal Ultrasonography

1.1K
Introduction:
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
This diagnostic tool allows the clinician to visually inspect internal structures within the abdomen, including vital organs such as the liver, gallbladder, pancreas, kidneys, and spleen.
The abdominal ultrasound process begins with applying a special gel to the patient's skin over the abdomen. This gel enhances the...
1.1K
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

468
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
468
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.6K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of Early Breast Cancer Response to Chemotherapy with Ultrasound Radiomics.

Diagnostics (Basel, Switzerland)·2026
Same author

Faster motion correction of clinical contrast-enhanced ultrasound imaging using deep learning.

IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium·2026
Same author

Multiparametric quantification and visualization of liver fat using ultrasound.

WFUMB ultrasound open·2026
Same author

Quantitative Multifrequency Ultrasound Imaging Using Narrowband Pulsing for Tissue Characterization.

Investigative radiology·2026
Same author

Minimal angular compounding required for coherence-based sound speed estimation with plane wave ultrasound imaging.

Ultrasonics·2025
Same author

Apolipoprotein E receptor 2 in endothelium promote glucose tolerance by mediating insulin delivery to skeletal muscle.

Molecular metabolism·2025

Related Experiment Video

Updated: Jan 4, 2026

Blood Flow Imaging with Ultrafast Doppler
05:57

Blood Flow Imaging with Ultrafast Doppler

Published on: October 14, 2020

8.2K

Contrast-enhanced ultrasound imaging using pulse inversion spectral deconvolution.

Mawia Khairalseed1, Ipek Oezdemir1, Kenneth Hoyt1

  • 1Department of Bioengineering, University of Texas at Dallas, Richardson, Texas 75080, USA.

The Journal of the Acoustical Society of America
|November 2, 2019
PubMed
Summary

Pulse inversion spectral deconvolution (PISD) enhances contrast-enhanced ultrasound (CEUS) imaging. This novel technique significantly improves contrast-to-tissue ratio and spatial resolution for clearer medical imaging.

More Related Videos

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
10:39

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound

Published on: March 4, 2015

15.8K
Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound
07:29

Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound

Published on: October 4, 2021

2.8K

Related Experiment Videos

Last Updated: Jan 4, 2026

Blood Flow Imaging with Ultrafast Doppler
05:57

Blood Flow Imaging with Ultrafast Doppler

Published on: October 14, 2020

8.2K
Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
10:39

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound

Published on: March 4, 2015

15.8K
Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound
07:29

Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound

Published on: October 4, 2021

2.8K

Area of Science:

  • Medical Imaging
  • Ultrasound Technology
  • Signal Processing

Background:

  • Contrast-enhanced ultrasound (CEUS) is vital for medical diagnostics.
  • Existing nonlinear imaging (NLI) methods face limitations in contrast-to-tissue ratio and spatial resolution.
  • Advanced signal processing is needed to improve CEUS performance.

Purpose of the Study:

  • Introduce and evaluate a novel CEUS imaging approach: pulse inversion spectral deconvolution (PISD).
  • Assess the efficacy of PISD in enhancing contrast-to-tissue ratio and spatial resolution compared to traditional NLI.
  • Determine the potential of PISD as a real-time CEUS postprocessing technique.

Main Methods:

  • Developed PISD using Gaussian-weighted Hermite polynomials for inverted pulse sequences.
  • Filtered ultrasound backscattered data to discriminate linear and nonlinear signal components.
  • Acquired data using a research ultrasound scanner with plane wave imaging and angular compounding (1-9 angles).
  • Evaluated imaging frequency (4.5-6.25 MHz) and mechanical index (0.1-0.3).

Main Results:

  • PISD demonstrated a nearly tenfold improvement in contrast-to-tissue ratio compared to NLI.
  • Spatial resolution was enhanced due to deconvolution and spatial angular compounding.
  • Preliminary in vitro and in vivo (mouse hindlimb) data supported PISD's effectiveness.

Conclusions:

  • PISD is a promising postprocessing technique for real-time CEUS imaging.
  • The method offers significant improvements in image quality metrics.
  • PISD has the potential to advance diagnostic capabilities in ultrasound.