Feasibility study of three-dimensional multiple-beam x-ray luminescence tomography

Area of Science:

• Medical Imaging
• Biomedical Engineering
• Physics

Background:

• X-ray luminescence tomography (XLT) offers high-resolution imaging using X-ray beams.
• Traditional fan-beam XLT systems face challenges with long data acquisition times due to scanning requirements.
• Improving spatial resolution and imaging efficiency in XLT is crucial for advanced applications.

Purpose of the Study:

• To develop a three-dimensional multiple-beam XLT imaging method.
• To enhance spatial resolution in both longitudinal and transverse directions.
• To reduce the data acquisition time compared to traditional scanning methods.

Main Methods:

• Implementation of an X-ray fence-modulation component to generate multiple X-ray beams.
• Development of a novel three-dimensional multiple-beam XLT system.
• Conducting single-source and double-source experiments to evaluate performance.

Main Results:

• Single-source experiments achieved 0.62 mm location error and 0.87 dice coefficient.
• Double-source experiments yielded 1.32 mm location error and 0.63 dice coefficient.
• Simulation experiments demonstrated superior results at various depths compared to traditional methods, with optimal performance at the smallest X-ray width.

Conclusions:

• The proposed three-dimensional multiple-beam XLT method significantly improves spatial resolution and imaging efficiency.
• The fence-modulation technique effectively generates multiple beams, enhancing imaging capabilities.
• This advanced XLT approach shows promise for more effective and faster medical imaging.