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Updated: Jan 4, 2026

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
Published on: October 2, 2018
Caffeate and piperidine-3-ol derivatives from the stem bark of Cassia sieberiana
Brice Cedric K Atontsa1, Gabin Thierry M Bitchagno1,2, James D Simo Mpetga1
1Department of Chemistry, University of Dschang, Dschang, Cameroon.
Abstract:
A new caffeate derivative from the ethanol extract of the stem bark of Cassia sieberiana DC. is described herein along with the known secondary metabolites spectaline (2), iso-6-cassine (3), 3-O-methyl-chiro-inositol (4), monobehenin (5), octyl nonadecyloate (6), β-sitosterol (7), stigmasterol (8) and sitosterol 3-O-β-D-glucopyranoside (9). The chemical structures were elucidated by means of various spectroscopic and spectrometric techniques. Extract and isolated compounds were devoid of inhibitory action against the herein selected bacterial strains (MICs > 256 μg/mL) but showed capacities to reduce 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (EC50 < 3 μg/mL) considerably better than the "gold standard" trolox (EC50 6.47 ± 0.48 μg/mL).
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