Related Experiment Video
Updated: Jan 4, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic
Brian Le1, Margaret Knoedler1, Gray Roberge1
1University of Wisconsin-Madison, Department of Urology, 1685 Highland Avenue, 3rd Floor, Madison, WI, 53705, USA.
Abstract:
Tranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control prostatic bleeding. This patient's hematuria abated with endoscopic localized injection of tranexamic acid into the prostate. The effects were durable with no bleeding recurrence reported while maintaining therapeutic anticoagulation.
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