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Updated: Jan 4, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
Hyperbaric oxygen therapy for perioperative posterior ischemic optic neuropathy: a case report
Hussain M Allashem1, Douglas G Sward2, Kinjal Sethuraman2
1Department of Emergency Medicine, University of Maryland Medical Center, Baltimore, Maryland U.S.
This study reports a successful treatment for postoperative posterior ischemic optic neuropathy (PION) using hyperbaric oxygen therapy. The patient experienced significant vision recovery, highlighting a promising therapeutic option for this rare condition.
Area of Science:
- Ophthalmology
- Neurology
- Hyperbaric Medicine
Background:
- Posterior ischemic optic neuropathy (PION) is a rare but serious complication following surgery, often leading to vision loss.
- Current treatment strategies for PION have shown mixed success, necessitating exploration of novel therapeutic approaches.
Observation:
- An elderly female patient developed bilateral vision loss post-angiography and hydralazine administration.
- The patient received hyperbaric oxygen therapy (HBOT) following a protocol for decompression sickness.
- Significant visual improvement was noted immediately after the first HBOT session and continued throughout treatment.
Findings:
- Hyperbaric oxygen therapy, in combination with systemic steroids, was effective in restoring vision in a patient with postoperative PION.
- The patient's vision returned to near baseline levels following the course of treatment.
Implications:
- This case suggests that hyperbaric oxygen therapy is a viable and potentially effective treatment for postoperative PION.
- Further research into HBOT for ischemic optic neuropathies is warranted given its promising results in this patient.
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