Exercise Interventions for Improving Flexibility in People with Multiple Sclerosis: A Systematic Review and...

Area of Science:

• Neurology
• Rehabilitation Science
• Exercise Physiology

Background:

• Multiple sclerosis (MS) frequently causes joint range of motion limitations, spasticity, and inactivity.
• Reduced flexibility in MS is associated with postural issues and muscle pain.
• Understanding exercise impacts on MS flexibility is crucial for rehabilitation.

Purpose of the Study:

• To systematically review and meta-analyze studies on exercise interventions for flexibility in people with MS.
• To assess the methodological quality and reporting standards of relevant research.
• To determine the effectiveness of exercise on flexibility and range of motion in MS.

Main Methods:

• Systematic search of MEDLINE/PubMed, SPORTDiscus, and Scopus databases up to May 2019.
• Inclusion of randomized controlled trials (RCTs) and uncontrolled studies on exercise and MS flexibility.
• Assessment of methodological quality using PEDro, QATB-AS, and reporting quality via CERT scale.

Main Results:

• Seven studies (4 RCTs, 3 uncontrolled) were included; RCT quality varied from poor to excellent.
• Uncontrolled studies showed fair to poor methodological quality.
• Meta-analysis revealed no significant improvements in hamstring flexibility or joint range of motion (hips, knees, ankles).

Conclusions:

• Individual studies suggest potential benefits of exercise for lower limb flexibility in MS.
• The meta-analysis did not corroborate these findings, indicating a need for higher-quality research.
• Current evidence on exercise efficacy for MS flexibility remains inconclusive.