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Published on: June 28, 2024
A rare case of intracranial extra-axial ependymoma
Viscardo Paolo Fabbri1, Valentina Papa2, Antonio Fioravanti3
1Department of Biomedical and Neuromotors Sciences, Anatomic Pathology at Bellaria Hospital, University of Bologna, Bologna, Italy.
Abstract:
Intracranial extra-axial ependymomas (IEAEs) are extremely uncommon tumors and they could have a wide spectrum of clinical and radiological features. Here we report morphological features of an extra-axial ependymoma (radiology, histology and ultrastructural details) which mimicked the presentation of meningioma.
Insights
Intracranial extra-axial ependymomas are rare tumors that can resemble meningiomas. This report details the radiological and histological features of an intracranial extra-axial ependymoma that mimicked a meningioma.
Area of Science:
- Neuro-oncology
- Pathology
- Radiology
Background:
- Intracranial extra-axial ependymomas (IEAEs) are exceptionally rare central nervous system tumors.
- Their clinical and radiological presentations can be highly variable, posing diagnostic challenges.
Observation:
- This report details a rare case of an intracranial extra-axial ependymoma.
- The tumor exhibited morphological features on radiology, histology, and ultrastructure that closely mimicked a meningioma.
Findings:
- The key finding is the presentation of an intracranial extra-axial ependymoma with features indistinguishable from a meningioma.
- Detailed morphological analysis (radiological, histological, ultrastructural) is crucial for accurate diagnosis.
Implications:
- Accurate differentiation of IEAEs from meningiomas is critical for appropriate treatment planning.
- This case highlights the importance of considering rare differential diagnoses in neuro-oncology.
- Enhanced understanding of IEAE morphology can improve diagnostic accuracy and patient outcomes.

