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Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
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[Type 1 autoimmune pancreatitis: a case report].
Jéssica Alférez Andía1, Harold Benites Goñi2, Alfonso Chacaltana Mendoza2
1Hospital Santa Rosa, Ministerio de Salud. Lima, Per ú.
Summary
Autoimmune pancreatitis (PAI) is a rare cause of obstructive jaundice. This case highlights the effectiveness of corticosteroid treatment for PAI, leading to complete resolution of symptoms and imaging findings.
Area of Science:
- Gastroenterology
- Immunology
- Oncology
Background:
- Autoimmune pancreatitis (PAI) is a rare inflammatory condition of the pancreas.
- It presents diagnostic challenges, often mimicking pancreatic cancer or biliary obstruction.
- PAI has distinct clinical, radiological, serological, and histopathological features.
Observation:
- A 62-year-old woman presented with abdominal pain, weight loss, and normal labs.
- Imaging revealed a diffusely enlarged pancreas with a peripancreatic halo and a heterogeneous lesion.
- Fine-needle aspiration showed lymphoplasmacytic infiltrate, and serum IgG4 levels were elevated (520 mg/dL).
Findings:
- The patient was diagnosed with probable type I autoimmune pancreatitis.
- A therapeutic trial of corticosteroids was initiated.
- Follow-up imaging at 4 weeks demonstrated an adequate treatment response.
Implications:
- This case underscores the importance of considering PAI in the differential diagnosis of pancreatic masses and jaundice.
- Corticosteroid therapy is an effective treatment for autoimmune pancreatitis.
- Early diagnosis and treatment can lead to complete resolution of PAI manifestations.
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