Jove
Visualize
Contact Us

Related Concept Videos

Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

4.1K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
4.1K
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

3.5K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.5K
Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

2.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.2K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.0K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.0K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.8K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.8K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

1.7K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterogeneity and clinical relevance of group 2 innate lymphoid cells subsets in nasal polyps.

The Journal of allergy and clinical immunology·2026
Same author

The Association Between Sinus Surgery and the Development of Asthma and Non-Cystic Fibrosis Bronchiectasis in Patients With Chronic Rhinosinusitis.

International forum of allergy & rhinology·2025
Same author

Effects of type 3 and neutrophilic inflammation on type 2 chronic rhinosinusitis with nasal polyps.

The Journal of allergy and clinical immunology·2025
Same author

Tezepelumab inhibits highly functional truncated thymic stromal lymphopoietin in chronic rhinosinusitis.

The Journal of allergy and clinical immunology·2025
Same author

Analysis of human neutrophils from nasal polyps by single-cell RNA sequencing reveals roles of neutrophils in chronic rhinosinusitis.

The Journal of allergy and clinical immunology·2024
Same author

Associations Between Chronic Rhinosinusitis and the Development of Non-Cystic Fibrosis Bronchiectasis.

The journal of allergy and clinical immunology. In practice·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jan 4, 2026

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
12:02

Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

Published on: May 2, 2018

12.9K

Occupational immunologic lung disease.

Dawn K Lei, Leslie C Grammer

    Allergy and Asthma Proceedings
    |November 7, 2019
    PubMed
    Summary

    Occupational immunologic lung diseases, including occupational asthma and hypersensitivity pneumonitis, stem from inhaling airborne agents at work. Understanding these conditions is crucial for worker health and safety.

    Area of Science:

    • Occupational Medicine
    • Pulmonology
    • Immunology

    Background:

    • Occupational immunologic lung disease involves lung responses to workplace airborne agents.
    • It includes immunologically mediated occupational asthma (OA) and hypersensitivity pneumonitis (HP).
    • Irritant-induced OA and reactive airways dysfunction syndrome (RADS) are non-immunologic entities.

    Purpose of the Study:

    • To review the characteristics and triggers of occupational immunologic lung diseases.
    • To differentiate between immunologic and non-immunologic occupational lung conditions.
    • To highlight high-risk occupations and causative agents.

    Main Methods:

    • Literature review of occupational immunologic lung diseases.
    • Classification of occupational asthma triggers (high-molecular-weight proteins and low-molecular-weight haptens).

    More Related Videos

    Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
    14:48

    Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

    Published on: March 21, 2021

    5.5K
    In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
    08:54

    In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

    Published on: October 22, 2019

    9.5K

    Related Experiment Videos

    Last Updated: Jan 4, 2026

    Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
    12:02

    Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA

    Published on: May 2, 2018

    12.9K
    Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury
    14:48

    Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

    Published on: March 21, 2021

    5.5K
    In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
    08:54

    In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

    Published on: October 22, 2019

    9.5K
  • Description of hypersensitivity pneumonitis presentations and diagnostic markers.

    • Main Results:

    • Occupational asthma can be triggered by allergens (HMW proteins) or haptens (LMW substances like isocyanates).
    • Hypersensitivity pneumonitis presents acutely, subacutely, or chronically, often with specific lymphocyte patterns in bronchoalveolar lavage.
    • High-risk occupations span agriculture, manufacturing, healthcare, and service industries.

    Conclusions:

    • Occupational asthma and hypersensitivity pneumonitis are distinct immunologic responses to inhaled workplace agents.
    • Recognition of causative agents and at-risk professions is key for prevention and management.
    • Understanding the immunologic mechanisms aids in diagnosing and treating these debilitating lung diseases.