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Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer

Haizhou Zhu1, Rosalin Mishra2, Long Yuan2

  • 1Figueroa, Prof. Dr. Edward. J. Merino* Department of Chemistry, McMicken College of Arts and Sciences, University of Cincinnati, Cincinnati, OH 45221, USA.

Chemmedchem
|November 8, 2019
PubMed

Keywords:
oxidative cyclizationphosphoinositide 3-kinase inhibitorsprodrugsreactive oxygen speciessynergy effects

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