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Mania and psychosis associated with right parietal meningioma

Emily Moore1, Anshuman A Srivastava1, Senthil Vel Rajan Rajaram Manoharan2

  • 1Rutgers New Jersey Medical School, Newark, NJ, USA.

International Journal of Psychiatry in Medicine
|November 9, 2019
PubMed
Abstract

Insights

This case report highlights a man with right parietal meningioma who developed mania and psychosis. It suggests a link between this specific brain tumor and manic symptoms.

Area of Science:

  • Neurology
  • Neuro-oncology
  • Psychiatry

Background:

  • Meningiomas are common primary central nervous system tumors.
  • Psychiatric changes like depression, apathy, psychosis, and personality changes are known associations.
  • The right parietal lobe is implicated in various cognitive and emotional functions.

Observation:

  • A 59-year-old male presented with headache and lower extremity weakness.
  • He had a medial sphenoidal wing meningioma (resected) and a right parietal meningioma (non-resected).
  • The non-resected right parietal meningioma increased in size over time.

Findings:

  • The patient developed mania with psychotic features.
  • These psychiatric symptoms coincided with the growth of the right parietal meningioma.
  • This is one of the first reports linking right parietal meningioma to mania and psychosis.

Implications:

  • Right parietal meningiomas may be associated with the development of mania and psychotic features.
  • Further research is needed to understand the neurobiological mechanisms.
  • This case underscores the importance of considering intracranial tumors in new-onset psychiatric disorders.
Keywords:
meningiomaneoplasmspsychiatrypsychotic disorders

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