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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

206
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
206
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

324
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
324
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

346
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
346
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

340
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
340
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

356
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
356
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

233
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
233

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Related Experiment Video

Updated: Jan 4, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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[Mitral Valve Replacement with the On-X Valve].

Kazuyoshi Doi1, Manabu Itoh, Ryo Noguchi

  • 1Department of Cardiovascular Surgery, Yanagawa Hospital, Yanagawa, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|November 9, 2019
PubMed
Summary

The On-X mechanical valve shows good midterm performance in mitral valve replacement patients, even after trauma or temporary anticoagulation discontinuation. These cases demonstrate its antithrombogenicity and durability up to 10 years.

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Mechanical Circulatory Support

Background:

  • Mitral valve replacement (MVR) is a critical procedure for managing severe mitral valve disease.

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  • Mechanical heart valves require lifelong anticoagulation to prevent thromboembolic events.
  • The On-X mechanical valve is designed for improved hemocompatibility and reduced thrombogenicity.