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Hydrolyzed Collagen-Sources and Applications.

Arely León-López1, Alejandro Morales-Peñaloza2, Víctor Manuel Martínez-Juárez1

  • 1Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Av. Universidad km 1. Ex Hacienda de Aquetzalpa. Tulancingo, Hidalgo 43600, Mexico.

Molecules (Basel, Switzerland)
|November 10, 2019
PubMed
Summary

Hydrolyzed collagen (HC) from marine sources offers a safer alternative to bovine or porcine sources. This review explores marine-derived HC types, extraction methods, and biomaterial applications.

Keywords:
antioxidant activitydenaturationhydrolysateshydrolyzed collagenpeptide

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Area of Science:

  • Biomaterials Science
  • Biochemistry
  • Food Science

Background:

  • Hydrolyzed collagen (HC) consists of low molecular weight peptides (3-6 KDa) derived from collagen.
  • Traditional sources like bovine and porcine collagen present health concerns.
  • Marine sources (skin, scale, bones) are emerging as viable alternatives with beneficial properties.

Purpose of the Study:

  • To review the different types of hydrolyzed collagen.
  • To explore various extraction sources for hydrolyzed collagen.
  • To discuss the applications of hydrolyzed collagen as a biomaterial.

Main Methods:

  • Enzymatic hydrolysis in acidic or alkaline conditions at controlled temperatures.
  • Extraction from diverse biological sources, focusing on marine origins.
  • Analysis of factors influencing HC properties like molecular weight and solubility.

Main Results:

  • Marine-derived HC exhibits promising properties, addressing limitations of conventional sources.
  • Extraction type and source significantly impact HC characteristics (molecular weight, solubility, activity).
  • HC finds broad utility across food, pharmaceutical, cosmetic, biomedical, and leather industries.

Conclusions:

  • Marine sources provide a safe and effective alternative for hydrolyzed collagen production.
  • Understanding extraction parameters is key to optimizing HC for specific applications.
  • Hydrolyzed collagen is a versatile biomaterial with expanding industrial relevance.