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Updated: Jan 4, 2026
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Repeatability and reproducibility of optical biometry implemented in a new optical coherence tomographer and
Piotr Kanclerz1, Kenneth J Hoffer2, Jos J Rozema3
1Hygeia Clinic, Gdańsk, Poland.
Purpose:
To examine the repeatability and reproducibility of biometry provided by a new anterior-posterior segment spectral-domain optical coherence tomography (SD-OCT) device (Revo NX) and compare it with that provided by a validated optical low-coherence reflectometry (OLCR) biometer (Lenstar LS 900).
Setting:
Hygeia Clinic, Gdańsk, Poland.
Design:
Prospective evaluation of diagnostic test.
Methods:
The axial length (AL), lens thickness (LT), central corneal thickness (CCT), and anterior chamber depth (ACD) (corneal epithelium to lens) were measured in eyes of volunteers. Two skilled operators obtained 3 measurements in random order with the SD-OCT device. Repeatability was calculated for each observer, while reproducibility was assessed by a change in observer. To compare agreement between the SD-OCT device and OLCR device, the first observer took 3 measurements with both devices.
Results:
The study evaluated 63 eyes of 63 volunteers. The mean AL measurement (+0.11 mm ± 0.02 [SD]) and mean ACD measurement (0.05 ± 0.04 mm) were significantly higher with the SD-OCT device than with the OLCR device; the CCT measurements did not differ between the devices. A very strong correlation was found for all parameters, while Bland-Altman analysis showed narrow 95% limits of agreement for AL (0.06 to 0.15 mm), ACD (-0.02 to 0.12 mm), LT (-0.23 to 0.17 mm), and CCT (-7.83 to 6.17 μm).
Conclusions:
The new SD-OCT device provided repeatable and reproducible AL, ACD, LT, and CCT measurements. The results with the SD-OCT device showed strong correlations with those obtained with the OLCR device. However, the AL and ACD measurements of the 2 devices cannot be considered interchangeable.
