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Management Strategies for Nocturia.

Danielle J Gordon1, Curran J Emeruwa2, Jeffrey P Weiss2

  • 1Department of Urology, SUNY Downstate College of Medicine, 450 Clarkson Avenue, Box 79, Brooklyn, NY, 11203, USA. danielle.gordon@downstate.edu.

Current Urology Reports
|November 11, 2019
PubMed
Summary
This summary is machine-generated.

Nocturia, or nighttime urination, management depends on its cause. Desmopressin effectively treats nocturnal polyuria, while other treatments show limited evidence for nocturia management.

Keywords:
Diminished bladder capacityGlobal polyuriaNocturiaNocturia managementNocturia treatmentNocturnal polyuria

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Area of Science:

  • Urology
  • Nephrology
  • Geriatrics

Background:

  • Nocturia is a common condition characterized by nighttime awakenings to urinate.
  • Its multifactorial pathophysiology presents management challenges.
  • Understanding the underlying causes is crucial for effective treatment.

Purpose of the Study:

  • To provide an overview of nocturia management strategies.
  • To summarize evidence for treating nocturia based on its etiologic categories.
  • To guide clinical decision-making for nocturia treatment.

Main Methods:

  • Literature review and evidence synthesis.
  • Categorization of nocturia by underlying mechanisms: nocturnal polyuria, diminished bladder capacity, global polyuria.
  • Evaluation of treatment efficacy for each category.

Main Results:

  • Behavioral modification is the first-line treatment for nocturia.
  • Desmopressin demonstrates high efficacy for nocturnal polyuria.
  • Evidence for alpha-blockers, antimuscarinics, and surgery in nocturia is limited, but they may help with associated lower urinary tract symptoms or overactive bladder.

Conclusions:

  • Nocturia treatment must be tailored to the specific underlying mechanism.
  • Desmopressin is a key therapy for nocturnal polyuria.
  • Further research is needed to clarify the role of other interventions.