Related Experiment Video
Updated: Jan 4, 2026
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI
Shijie C Zheng1, Charles E Breeze2, Stephan Beck3
1CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai, China.
Summary:
It is well recognized that cell-type heterogeneity hampers the interpretation of Epigenome-Wide Association Studies (EWAS). Many tools have emerged to address this issue, including several R/Bioconductor packages that infer cell-type composition. Here we present a web application for cell-type deconvolution, which offers the functionality of our EpiDISH Bioconductor/R package in a user-friendly GUI environment. Users can upload their data to infer cell-type composition and differentially methylated cytosines in individual cell-types (DMCTs) for a range of different tissues.
Availability And Implementation:
EpiDISH web server is implemented with Shiny in R, and is freely available at https://www.biosino.org/EpiDISH/.
