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DNA Damage Prediction Tool in Dilated Cardiomyopathy: Don't Go Breaking My Heart

Jesus Jimenez1,2, Stacey L Rentschler1,2

  • 1Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, Missouri.

JACC. Basic to Translational Science
|November 13, 2019
PubMed
Abstract

No abstract available in PubMed .

Keywords:
DNA damagePARdilated cardiomyopathystratification

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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