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ImageDataExtractor: A Tool To Extract and Quantify Data from Microscopy Images.

Karim T Mukaddem1, Edward J Beard1,2, Batuhan Yildirim1

  • 1Cavendish Laboratory, Department of Physics, University of Cambridge, J. J. Thomson Avenue, Cambridge CB3 0HE, U.K.

Journal of Chemical Information and Modeling
|November 13, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces ImageDataExtractor, a toolkit that automatically extracts quantitative particle size and shape data from scientific microscopy images. This facilitates large-scale data generation for data-driven materials discovery and prediction.

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Area of Science:

  • Materials Science
  • Data Science
  • Nanotechnology
  • Scientific Image Analysis

Background:

  • Data-driven materials discovery relies on large datasets of chemical structure and property information.
  • Microscopy images are crucial for characterizing nanoparticle size and shape but are often fragmented and qualitative in scientific literature.
  • Existing data sources lack the quantitative, large-scale information needed for advanced materials prediction.

Purpose of the Study:

  • To develop a toolkit for automated extraction of quantitative data from microscopy images.
  • To enable the generation of large datasets of nanoparticle size and shape information.
  • To support data-driven materials discovery by providing accessible, analyzed image data.

Main Methods:

  • The ImageDataExtractor toolkit automatically identifies and extracts microscopy images from scientific documents.
  • It decodes scale bar information using optical character recognition and super-resolution convolutional neural networks.
  • Particle detection and profiling are performed using thresholding, segmentation, polygon fitting, and edge correction algorithms.

Main Results:

  • The toolkit successfully automates the extraction of quantitative particle size and shape data from microscopy images.
  • Evaluation metrics show precision and recall greater than 80% for most image processing steps.
  • Precision exceeds 80% for all critical data extraction steps.

Conclusions:

  • ImageDataExtractor can generate large-scale, quantitative particle datasets essential for data-driven materials discovery.
  • The toolkit's high-throughput capability addresses the need for structured data from fragmented microscopy literature.
  • The tool is available under the MIT license, promoting wider use in scientific research.