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Does tranexamic acid improve intra-operative visualisation in endoscopic ear surgery? A double-blind, randomised,
1Department of Otorhinolaryngology and Head Neck Surgery, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, India.
The Journal of Laryngology and Otology
|November 14, 2019
Summary
Tranexamic acid improved surgical field visualization during endoscopic ear surgery by reducing intra-operative bleeding, particularly in the external auditory canal. This makes it an effective hemostatic agent for these procedures.
Area of Science:
- Otolaryngology
- Surgical Hemostasis
- Minimally Invasive Surgery
Background:
- Endoscopic ear surgery requires clear visualization, which can be hindered by intra-operative bleeding.
- Effective hemostasis is crucial for successful outcomes in otologic procedures.
Purpose of the Study:
- To evaluate the efficacy of tranexamic acid in controlling intra-operative bleeding.
- To assess the impact of tranexamic acid on surgical field visualization during endoscopic ear surgery.
Main Methods:
- A randomized controlled trial involving 50 patients undergoing endoscopic ear surgery.
- Patients received either tranexamic acid or normal saline.
- Bleeding and field visibility were assessed using the Das and Mitra endoscopic ear surgery score for the external auditory canal and middle ear.
Main Results:
- Tranexamic acid significantly improved the Das and Mitra score in the external auditory canal (p < 0.05).
- No significant difference in scores was observed for the middle ear.
- Mean arterial pressure, heart rate, and surgical duration were comparable between groups.
Conclusions:
- Tranexamic acid is an effective hemostatic agent in endoscopic ear surgery.
- It particularly enhances surgical field visualization during manipulation of the external auditory canal.
- The findings support the use of tranexamic acid to improve operative conditions in otologic procedures.
