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Rheumatoid vasculitis with intrarenal aneurysm formation
L Moreland1, A DiBartolomeo, J Brick
1Department of Medicine, West Virginia University School of Medicine, Morgantown.
The Journal of Rheumatology
|January 1, 1988
Summary
Rheumatoid arthritis (RA) can rarely cause kidney vasculitis. This case highlights intrarenal aneurysms as a key finding in RA-associated renal vasculitis, confirmed by arteriography and autopsy.
Area of Science:
- Nephrology
- Rheumatology
- Pathology
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune disease primarily affecting joints.
- While systemic vasculitis can occur in severe RA, clinical renal involvement is infrequent.
- High rheumatoid factor titers are associated with RA complications.
Observation:
- A 58-year-old male with an 8-year history of seropositive erosive RA presented with acute abdominal pain and syncope.
- Arteriography revealed intrarenal saccular aneurysms, leading to a diagnosis of vasculitis.
- Autopsy confirmed the coexistence of RA and renal vasculitis.
Findings:
- This case documents intrarenal aneurysm formation in a patient with rheumatoid arthritis-associated vasculitis.
- Arteriographic findings of intrarenal aneurysms are presented for the first time in this context.
- Autopsy findings provided definitive evidence of renal vasculitis linked to RA.
Implications:
- Highlights the importance of considering renal vasculitis in RA patients with severe symptoms.
- Suggests intrarenal aneurysms may be a specific arteriographic marker for RA-related renal vasculitis.
- Underscores the need for early diagnosis and management of renal complications in severe RA.