The surface immunoglobulin receptors of human lymphocytes in pollinosis
Abstract:
The immunological reaction of immediate as well as delayed type is produced in patients with pollinosis by the contact with pollen allergens. The immunological disturbances partially connected with function of T and B lymphocytes can be treated as the basal mechanism of pollinosis. The presence of surface immunoglobulins (SIg) from classes IgA, IgG and IgM on the B lymphocytes in circulating blood from the patients with pollinosis in various stages of the disease were studied. The method of direct immunofluorescence was used. The decrease of B lymphocytes with SIg of IgG was found. On the basis of presence SIg (IgA, IgG, IgM) on lymphocytes the four periods of various immunological reaction in pollinosis were differentiated: I - primary immunological response, II - secondary immunological response, III - immunological exhaust, IV - immunological stabilization.
More Related Videos
06:15Characterization of Thymus-dependent and Thymus-independent Immunoglobulin Isotype Responses in Mice Using Enzyme-linked Immunosorbent Assay
Published on: September 7, 2018
08:25Unraveling Key Players of Humoral Immunity: Advanced and Optimized Lymphocyte Isolation Protocol from Murine Peyer's Patches
Published on: November 21, 2018
Related Concept Videos
01:36Humoral Immune Responses
01:10Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
01:18Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
01:26Antigens Involved in Adaptive Immunity
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
01:28Diversity of Antigen Receptors
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
01:24B Cell Activation and Differentiation
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...