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Updated: Jan 3, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Adrenocortical carcinoma: Impact of surgical treatment
Eric Mirallié1, Claire Blanchard1, Cécile Caillard1
1Clinique de chirurgie digestive et endocrinienne, IMAD, Hôtel Dieu, CHU de Nantes, place Alexis-Ricordeau, 44093 Nantes cedex 01, France.
Abstract:
Compared to benign adrenal lesions, secreting or otherwise, malignant adrenocortical carcinoma is rare. Overall prognosis is poor, with <50% 5-year survival. Various prognostic factors have been identified, some tumor-related and others directly linked to surgical treatment. Surgery is the only possible curative treatment, and is decided upon in a multidisciplinary medical-surgical team meeting. Surgical approach (laparotomy vs. laparoscopy) remains a matter of debate. In the light of a recent literature search, the present review reassesses the prognostic criteria of surgical resection, the quality of which determines overall and recurrence-free survival.
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