Related Experiment Video
Updated: Jan 3, 2026

Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila
Published on: October 20, 2017
Glial SIK3: A central player in ion and volume homeostasis in Drosophila peripheral nerves
Uri Kahanovitch1, Michelle L Olsen2
1School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA.
Abstract:
The electrical properties of neuronal cells rely on gradients of ions across their membranes and the extracellular fluid (ECF) in which they are bathed. Little is known regarding how the ECF volume and content is maintained. In this issue, Li et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201907138) identify the kinase SIK3 in glia as a key signal transduction regulator in ion and volume homeostasis in Drosophila peripheral nerves.
Related Concept Videos
Glial Cells
Nervous Tissue: Glial Cells
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...

