Massive retroperitoneal aortoiliac aneurysm rupture revealing chronic Q fever
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Updated: Jan 3, 2026

The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii
Published on: April 18, 2016
Lin-Pierre Zhao1, Quentin Pellenc2, Nicoletta Pasi3
1Département de Médecine Interne, Hôpital Bichat, Université Paris Diderot, PRES Sorbonne Paris Cité, Assistance Publique Hôpitaux de Paris, Paris, France.
Abstract:
Chronic Coxiella burnetii vascular infection is rare and usually develops on a pre-existing vascular lesion, such as an aneurysm or vascular prosthesis. We report a case of proven C. burnetii aortic infection revealed by a massive retroperitoneal aortoiliac aneurysm rupture in a patient at apparent low risk for chronic Q fever. Emergency treatment consisted of resection of the infected aneurysm and replacement with an in situ graft angioplasty. Doxycycline and hydroxychloroquine therapy was started postoperatively. After 6 months of follow-up, the patient had no signs of infection, and C. burnetii serologic antibody titers had significantly decreased.
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