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Tibial bypass salvage with eptifibatide in a patient with thrombocythemia

John Byrne1, Elisa Greco1, Erik Yeo2

  • 1Division of Vascular Surgery, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Journal of Vascular Surgery Cases
|November 15, 2019
PubMed

Early graft failure is a complex and challenging clinical condition faced by vascular surgeons performing infrainguinal bypass surgery. This case describes a patient with undiagnosed thrombocytosis undergoing urgent open revascularization for critical limb ischemia. The operative case was complicated by recurrent on-table acute thrombosis that was successfully managed with intravenous glycoprotein IIb/IIIa antagonism with eptifibatide. This is a novel case of its use for on-table salvage of an infrainguinal bypass graft. This case report outlines this challenging clinical problem and a novel use for glycoprotein IIb/IIIa antagonists.

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