Brainstem reflexes in neuro-Behçet disease
Yasemin Akıncı1, Furkan Asan1, Melis Sohtaoğlu1
1Istanbul University-Cerrahpasa, Cerrahpaşa School of Medicine, Department of Neurology, Istanbul, 34098, Turkey.
Neurophysiologie Clinique = Clinical Neurophysiology
|November 16, 2019
Summary
Neurophysiological tests like blink reflex showed poor sensitivity in detecting brainstem changes in neuro-Behçet Disease (NBD). These methods were less effective than neuroimaging for diagnosing brainstem lesions in NBD patients.
Area of Science:
- Neurology
- Neurophysiology
Background:
- Neuro-Behçet Disease (NBD) can affect the brainstem.
- Detecting functional brainstem changes in NBD is crucial for diagnosis and management.
Purpose of the Study:
- To evaluate the sensitivity of specific neurophysiological tests in detecting brainstem abnormalities in patients with NBD.
- To compare the diagnostic utility of these tests with neuroimaging.
Main Methods:
- Electrically-induced blink reflex (eBR), auditory blink reflex (aBR), and electrically-induced masseter inhibitory reflex (eMIR) were recorded.
- Tests were performed on 16 patients diagnosed with NBD.
Main Results:
- Neurophysiological tests demonstrated poor overall sensitivity for diagnosing brainstem lesions in NBD patients compared to neuroimaging.
- These tests also exhibited low sensitivity in differentiating between focal pontine lesions and diffuse brainstem disease in NBD.
Conclusions:
- Standard neurophysiological tests like eBR, aBR, and eMIR have limited value in detecting brainstem lesions in NBD.
- Neuroimaging remains a more sensitive tool for diagnosing brainstem involvement in NBD.
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