Gestational diabetes prevention and treatment: a protocol for developing core outcome sets

Area of Science:

• Obstetrics and Gynecology
• Clinical Trial Methodology
• Evidence-Based Medicine

Background:

• Selective reporting and outcome inconsistency in gestational diabetes mellitus (GDM) research limit clinical value.
• Current research practices hinder effective prevention and treatment strategies for GDM.
• There is a need for standardized outcome measures in GDM research.

Purpose of the Study:

• To present a study protocol for developing core outcome sets (COSs) for GDM.
• To address limitations in GDM research by establishing standardized outcome reporting.
• To enhance the efficiency and relevance of GDM prevention and treatment studies.

Main Methods:

• A three-phase project involving a systematic literature review.
• A three-round, web-based e-Delphi survey with key stakeholders for outcome prioritization.
• A consensus meeting to finalize the core outcome sets for GDM.

Main Results:

• The study protocol is established for developing GDM COSs.
• Outcome lists from systematic reviews and trials will be generated.
• Stakeholder consensus will be achieved through a structured Delphi process and meeting.

Conclusions:

• The developed COSs will standardize outcome reporting in GDM research.
• This initiative aims to improve the quality and applicability of GDM studies.
• Standardized outcomes will benefit both GDM prevention and treatment research.