Related Experiment Video
Updated: Jan 3, 2026
07:04
Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
Published on: April 15, 2021
2.4K
Systemic Artery Aneurysms and Kawasaki Disease
Qu-Ming Zhao1,2, Chen Chu1,2, Lin Wu1
1Children's Hospital of Fudan University, Shanghai, China; and.
Pediatrics
|November 17, 2019
Summary
Systemic artery aneurysms (SAAs) occurred in 14.2% of Kawasaki disease (KD) patients screened. Most SAAs showed significant regression within six months, indicating a favorable short-term outcome.
Area of Science:
- Cardiology
- Pediatric Rheumatology
- Vascular Medicine
Background:
- Coronary artery aneurysms (CAAs) are a known Kawasaki disease (KD) complication.
- Data on systemic artery aneurysms (SAAs) in KD are limited in the current era.
Purpose of the Study:
- To determine the incidence and early outcomes of SAAs in KD patients.
- To analyze SAA development in relation to CAAs.
Main Methods:
- Screened 162 KD patients at risk for SAAs using magnetic resonance angiography or peripheral angiography.
- Analyzed incidence and early outcomes of SAAs from April 2016 to March 2019.
Main Results:
- SAAs detected in 14.2% of screened KD patients (23/162) at 1 month post-onset.
- 2% of all KD patients (23/1148) had SAAs; median age at onset was 5 months.
- 129 SAAs found in 17 arteries; common sites include axillary, common iliac, and brachial arteries. High regression rate (92.9%) observed within 6 months.
Conclusions:
- SAAs in KD patients have a notable incidence.
- SAAs demonstrate a high rate of regression during short-term follow-up.
Related Concept Videos
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
163
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
163
01:30Aneurysm I: Introduction
240
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
240
01:26Aneurysm III: Interprofessional Care
227
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
227
01:23Rheumatic Heart Disease I: Introduction
383
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
383
01:11Overview of Systemic Arteries
1.5K
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
1.5K
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
408
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
408