Related Experiment Video
Updated: Jan 3, 2026
07:39
An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
Published on: August 15, 2012
14.1K
Tissue Parasites in HIV Infection
Eva H Clark1,2, Jose A Serpa3
1Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA. eva.clark@bcm.edu.
Current Infectious Disease Reports
|November 18, 2019
Summary
HIV and tissue parasite co-infections present complex interactions, influencing transmission, disease severity, and treatment outcomes. Understanding these dynamics is crucial for managing infections in people living with HIV.
Area of Science:
- Immunology
- Infectious Diseases
- Public Health
Background:
- Co-infection with HIV and tissue parasites is a significant global health concern, particularly in resource-limited settings.
- The clinical manifestations and outcomes of these co-infections are highly variable, depending on the specific parasite and the host's immune status.
Purpose of the Study:
- To review current knowledge on HIV and tissue parasite co-infections.
- To discuss transmission enhancement, clinical characteristics, treatment challenges, and outcomes.
- To highlight the importance of disseminating this information to healthcare providers.
Main Methods:
- This is a review article, synthesizing existing published data.
- Literature search and analysis of studies on HIV and tissue parasite co-infections.
Main Results:
- Only a few tissue parasites, mainly protozoa like malaria and leishmaniasis, are well-described in people living with HIV (PLWH).
- Interactions are variable: some parasites (e.g., Schistosoma) enhance HIV transmission, while HIV can worsen parasite presentation and treatment.
- Uncontrolled HIV infection complicates the management of various tissue parasitic infections.
Conclusions:
- Further research is needed to fully elucidate the complex interactions between HIV and tissue parasites.
- Disseminating current knowledge is vital for effective prevention, treatment, and control of these co-infections in PLWH.
- Healthcare providers need updated information to manage co-infected individuals effectively.
More Related Videos
Related Concept Videos
01:26Sexually Transmitted Infections
818
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
818
01:10Retrovirus Life Cycles
49.1K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
49.1K
01:29Pulmonary Tuberculosis I
788
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
788