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Perisilicone proliferation after vitrectomy for proliferative vitreoretinopathy
H Lewis1, J M Burke, G W Abrams
1Department of Ophthalmology, Medical College of Wisconsin, Milwaukee.
Ophthalmology
|May 1, 1988
Summary
Silicone oil injections for retinal detachment (RD) with proliferative vitreoretinopathy (PVR) frequently caused perisilicone proliferation (PSP). This complication led to recurrent RD and vision loss in many patients.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Silicone oil is used for retinal tamponade in complex retinal detachment.
- Proliferative vitreoretinopathy (PVR) presents a significant challenge in retinal detachment repair.
Purpose of the Study:
- To evaluate the incidence and characteristics of perisilicone proliferation (PSP) after silicone oil tamponade for advanced proliferative vitreoretinopathy (PVR).
Main Methods:
- Retrospective analysis of 31 patients treated with silicone oil for RD and PVR between 1983 and 1986.
- Clinical and histological examination of periproliferative membranes.
Main Results:
- Perisilicone proliferation (PSP) occurred in 61% of eyes, leading to recurrent retinal detachment (RD) in 49%.
- PSP manifested as preretinal membranes containing silicone oil, necrotic cells, and retinal cells.
- Silicone oil persisted in membranes even after intraocular removal.
Conclusions:
- Silicone oil tamponade for recurrent PVR is associated with a high risk of PSP.
- PSP frequently causes recurrent RD and visual impairment, highlighting a significant complication of this treatment.