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Updated: Jan 3, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Esophageal Dysphagia in the Elderly
Megan Q Chan1, Gokulakishnan Balasubramanian2
1Department of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, 395 W. 12th Avenue, 2nd floor, Columbus, OH, USA.
Recent advances in managing esophageal dysphagia include novel diagnostic tools and treatments like Peroral Endoscopic Myotomy (POEM). Personalized approaches are key for elderly patients facing this growing concern.
Area of Science:
- Gastroenterology
- Geriatric Medicine
- Medical Technology
Background:
- Dysphagia is a significant health issue in the aging global population.
- Increased prevalence of reflux disease contributes to dysphagia from peptic strictures and esophageal cancer.
- Dysphagia can lead to severe complications like malnutrition and aspiration pneumonia.
Purpose of the Study:
- To review recent advancements in the diagnosis and management of esophageal dysphagia.
- To highlight emerging challenges and therapeutic strategies for esophageal dysphagia in the elderly.
Main Methods:
- Review of current literature on esophageal dysphagia.
- Evaluation of novel diagnostic techniques, including endoscopic functional luminal imaging probe.
- Assessment of emerging and established treatment modalities for esophageal dysphagia.
Main Results:
- Endoscopic functional luminal imaging probe offers complementary diagnostic value.
- Opioid-induced esophageal dysfunction (OIED) is an emerging condition mimicking achalasia.
- Advanced treatments include intralesional steroid injections, electrosurgical incision, esophageal stents, and Peroral Endoscopic Myotomy (POEM).
Conclusions:
- A personalized treatment strategy, considering risks and benefits, is essential for managing esophageal dysphagia.
- Peroral Endoscopic Myotomy (POEM) shows promise for achalasia and spastic esophageal disorders.
- Further research is needed to establish optimal treatments for OIED and other spastic esophageal conditions.
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