Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teeth01:15

Teeth

1.5K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.5K
Analgesia and Pain Management01:25

Analgesia and Pain Management

1.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.4K
Tooth Anatomy01:21

Tooth Anatomy

1.9K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
1.9K
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

11.0K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
11.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation Between Osseous Degenerative Changes on Cone Beam Computed Tomography and Disc Displacement on Magnetic Resonance Imaging in Temporomandibular Joint Osteoarthritis.

Acta stomatologica Croatica·2026
Same author

Neurological Symptoms as (Post) Pandemic Burden in Children and Adolescents-Single Tertiary Center Experience from Croatia.

Iranian journal of child neurology·2026
Same author

Real-world effectiveness and safety of ofatumumab in relapsing multiple sclerosis: A multicenter cohort study.

Multiple sclerosis and related disorders·2026
Same author

Real-World Laboratory Analysis of Molecular Biomarkers in Multiple Sclerosis Centers in Central-Eastern European Countries Covering 107 Million Inhabitants.

International journal of molecular sciences·2025
Same author

Use of transcutaneous electrical nerve stimulation (TENS) to reduce anxiety in pediatric dentistry.

Dental and medical problems·2025
Same author

Ceftriaxone-loaded albumin-based nanoparticles incorporated into in situ ionic sensitive nasal gels: Development, characterization, and nasal drug deposition studies.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2025

Related Experiment Video

Updated: Jan 3, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
07:39

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

Published on: July 26, 2022

4.1K

OROFACIAL PAIN - DIAGNOSTIC AND THERAPEUTIC CHALLENGES.

Tomislav Badel1, Dijana Zadravec1, Vanja Bašić Kes1

  • 11Department of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia; 2Department of Diagnostic and Interventional Radiology, Sestre milosrdnice University Hospital Center, University of Zagreb, Zagreb, Croatia; 3Department of Neurology, Sestre milosrdnice University Hospital Center, University of Zagreb, Zagreb, Croatia; 4Psychiatry Hospital "Sv Ivan", Zagreb, Croatia; 5Academy of Medical Sciences of Croatia, Department of Public Health, Zagreb, Croatia; 6Department of Orthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

Acta Clinica Croatica
|November 20, 2019
PubMed
Summary

This study on orofacial pain found higher anxiety levels correlate with pain intensity. Multidisciplinary diagnostics and treatments like splints and anticonvulsants were evaluated for temporomandibular joint disorders and trigeminal neuralgia.

Keywords:
anxietyorofacial paintemporomandibular jointtrigeminal neuralgia

More Related Videos

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
06:37

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice

Published on: September 13, 2024

1.7K
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

331

Related Experiment Videos

Last Updated: Jan 3, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
07:39

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay

Published on: July 26, 2022

4.1K
Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
06:37

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice

Published on: September 13, 2024

1.7K
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

331

Area of Science:

  • Dentistry
  • Neurology
  • Pain Management

Background:

  • Orofacial pain, excluding odontogenic and malignant causes, is a complex clinical problem.
  • The diagnostics and therapy of stomatognathic system diseases have evolved over decades.
  • Multidisciplinary approaches are crucial for understanding and treating orofacial pain.

Purpose of the Study:

  • To evaluate the results of clinical diagnosis in patients with orofacial pain using a multidisciplinary approach.
  • To analyze the prevalence of anxiety and its correlation with pain intensity.
  • To assess the effectiveness of different therapeutic strategies for temporomandibular joint (TMJ) disorders and trigeminal neuralgia.

Main Methods:

  • Clinical diagnosis of 557 consecutive patients with orofacial pain.
  • Multidisciplinary diagnostic evaluation.
  • Statistical analysis of patient demographics, anxiety levels (STAI 1 and STAI 2), pain intensity (Visual Analogue Scale), and treatment outcomes.

Main Results:

  • 15.6% of patients dropped out; dropouts were significantly older.
  • Elevated anxiety levels were found in 84.4% of participating patients, correlating significantly with pain intensity (p<0.0001).
  • Michigan stabilization splints were common for TMJ disc displacement and osteoarthritis; anticonvulsants were primary for trigeminal neuralgia.

Conclusions:

  • Multidisciplinary cooperation is vital for accurate diagnosis and treatment of orofacial pain.
  • Anxiety is a significant factor in orofacial pain intensity.
  • Specific therapies, including splints, physiotherapy, anticonvulsants, and acupuncture, show utility for different orofacial pain conditions.