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A single factor dominates the behavior of rhythmic genes in mouse organs

Yang Cheng1, Yuhao Chi1, Luoying Zhang2

  • 1CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China, Shanghai, 200031, China.

BMC Genomics
|November 22, 2019
PubMed
Summary

Gene expression level is the primary driver of circadian rhythmicity across mouse organs. Higher expression correlates with greater rhythmic amplitude, suggesting an energy-saving mechanism in transcriptional regulation.

Keywords:
Circadian rhythmEnergy costRhythmic gene functionRhythmically expressed gene

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