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Updated: Jan 3, 2026

The ITS2 Database
Published on: March 12, 2012
The Swedish Twin Registry: Content and Management as a Research Infrastructure
Ulrika Zagai1, Paul Lichtenstein1, Nancy L Pedersen1
1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Abstract:
The Swedish Twin Registry functions as research infrastructure containing information on 216,258 twins born between 1886 and 2015, of whom 86,199 pairs have zygosity determined by DNA, an intrapair similarity algorithm, or being of opposite sex. In essence, practically all twins alive and currently 9 years or older have been invited for participation and donation of DNA on which genomewide single nucleotide polymorphisms array genotyping has been performed. Content, management and alternatives for future improvements are discussed.
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