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Epidural lipomatosis.

D J Quint1, R S Boulos, W P Sanders

  • 1Department of Neuroradiology, Henry Ford Hospital, Detroit, MI.

Radiology
|November 1, 1988
PubMed
Summary
This summary is machine-generated.

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Epidural lipomatosis, characterized by excess spinal fat, can cause neurological deficits. This study highlights its association with chronic steroid use and emphasizes advanced imaging like CT or MR for accurate diagnosis.

Area of Science:

  • Neurology
  • Radiology
  • Pathology

Background:

  • Epidural lipomatosis is a rare condition involving excessive extradural fat in the spinal canal.
  • It can lead to spinal cord compression and significant neurological deficits.
  • Chronic steroid use is a potential contributing factor.

Purpose of the Study:

  • To report new cases of epidural lipomatosis.
  • To evaluate diagnostic imaging modalities for this condition.
  • To correlate clinical findings with imaging and histology.

Main Methods:

  • Case series of six patients with epidural lipomatosis.
  • Diagnostic imaging included myelography, postmyelography computed tomography (CT), and magnetic resonance (MR) imaging.
  • Surgical exploration and histological examination were performed.

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Main Results:

  • Five of six patients had a history of chronic steroid use.
  • Postmyelography CT and MR imaging effectively identified increased extradural fat, even when myelography was normal.
  • Histological examination confirmed unencapsulated, normal fat in surgically treated patients.

Conclusions:

  • Epidural lipomatosis diagnosis requires a combination of clinical, imaging, surgical, and histological findings.
  • Advanced imaging (CT, MR) is crucial for diagnosis, especially when myelography is inconclusive.
  • Consider advanced imaging in cases of high clinical suspicion for epidural lipomatosis.