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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

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Optimizing Narrowband UVB Phototherapy Regimens for Psoriasis.

Rebecca L Yanovsky¹, Kathie P Huang², Elizabeth A Buzney²

¹Tufts University School of Medicine, 145 Harrison Avenue, Boston, MA 02111, USA.

Dermatologic Clinics

|November 23, 2019

Summary

Narrowband UVB (NBUVB) phototherapy is an effective treatment for psoriasis. This review discusses NBUVB protocols and new guidelines for physicians, including home-based and combination therapies.

Keywords:

Narrowband UVB Phototherapy Protocol optimization Psoriasis

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Area of Science:

Dermatology
Photomedicine

Background:

Psoriasis is a chronic autoimmune disease causing abnormal skin cell growth.
It affects approximately 3.2% of US adults.
Narrowband UVB (NBUVB) phototherapy is a standard first-line treatment for generalized plaque psoriasis.

Purpose of the Study:

To review fundamental considerations for physicians using NBUVB phototherapy.
To highlight updated guideline recommendations for psoriasis phototherapy.
To discuss advances in NBUVB treatment, including home phototherapy and combination therapies.

Main Methods:

Review of current literature and guideline recommendations for NBUVB phototherapy.
Comparison of NBUVB treatment protocols: initiation, dose escalation, and maintenance.
Discussion of emerging trends in psoriasis phototherapy.

Main Results:

NBUVB is a well-established and effective treatment for plaque psoriasis.
Updated guidelines provide refined protocols for NBUVB therapy.
Home phototherapy and combination treatments show promise for enhanced efficacy and convenience.

Conclusions:

Physicians should be aware of updated NBUVB guidelines for optimal psoriasis management.
Advances in phototherapy offer new possibilities for psoriasis treatment.
Further research into home and combination therapies is warranted.