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Phototherapy for Itch.

Connie S Zhong1, Sarina B Elmariah2

  • 1Harvard Medical School, 25 Shattuck Street, Boston, MA, 02115, USA.

Dermatologic Clinics
|November 23, 2019
PubMed
Summary
This summary is machine-generated.

Phototherapy effectively treats various types of pruritus (itch) by modulating the immune system and nerves. While generally safe, potential side effects like redness and worsened itching exist, and patient access can be a barrier.

Keywords:
ItchPUVAPhototherapyPrurigoPruritusUVAUVB

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Area of Science:

  • Dermatology
  • Photomedicine

Background:

  • Pruritus, or itch, is a common symptom across many dermatological conditions.
  • Phototherapy offers a non-systemic treatment option for various skin disorders.

Purpose of the Study:

  • To review the efficacy of phototherapy for inflammatory and non-inflammatory pruritic conditions.
  • To discuss the mechanisms, side effects, and patient barriers associated with phototherapy for itch.

Main Methods:

  • Literature review of phototherapy's application in pruritic conditions.
  • Analysis of immune suppression and neural modulation as mechanisms of action.

Main Results:

  • Phototherapy demonstrates efficacy in managing diverse pruritic conditions.
  • Common side effects include erythema and temporary pruritus exacerbation.

Conclusions:

  • Phototherapy is a viable, relatively safe skin-directed treatment for chronic itch.
  • Patient-specific barriers may limit the accessibility and application of phototherapy.