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Magnetic Resonance in Crohn Disease: Imaging Biomarkers in Assessing Response to Therapy
Jordi Rimola1, Nunzia Capozzi2
1Department of Radiology, Hospital Clínic Barcelona, Barcelona, Catalonia, Spain; CIBER-EHD, Barcelona, Catalonia, Spain; University of Barcelona, Barcelona, Catalonia, Spain.
Abstract:
The management of Crohn disease (CD) has entered a new era in which it is imperative to incorporate objective data and symptoms to plan the best therapeutic approach for each patient. Magnetic resonance (MR) imaging provides powerful objective insights into the disease process, and its high sensitivity and specificity for detecting inflammation make it essential for diagnosis and management. Growing evidence indicates that MR provides reliable and accurate information that enables detection of changes after treatment with biological drugs. This article provides an overview of currently established and emerging MR biomarkers for assessing response to treatment in patients with CD.
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