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Secondary Diffuse Large B-cell Lymphoma Mimicking Meningioma
Miguel Garcia-Grimshaw1, Diego Posadas-Pinto1, Jesus Delgado-de la Mora2
1Neurology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Ciudad de Mexico, MEX.
Cureus
|November 23, 2019
Summary
Meningiomas are common brain tumors. This case highlights how lymphoma can mimic meningioma on brain imaging, emphasizing the need for careful diagnosis.
Area of Science:
- Neurology
- Radiology
- Oncology
Background:
- Meningiomas are the most common primary central nervous system (CNS) tumors, typically benign and extra-axial.
- Neuroimaging, particularly Magnetic Resonance Imaging (MRI), shows characteristic features like T1 isointensity, T2 hyperintensity, and avid contrast enhancement.
- The 'dural tail sign' is a common finding but not pathognomonic, as other lesions can present similarly.
Observation:
- A case is presented of a woman with central nervous system involvement of non-Hodgkin lymphoma.
- The lymphoma manifested as a dural mass with imaging characteristics that closely resembled a meningioma.
- This presentation underscores the potential for misdiagnosis based solely on imaging findings.
Findings:
- The dural mass in this case mimicked typical meningioma imaging features.
- Differential diagnosis is crucial when neuroimaging findings are not entirely specific.
- Distinguishing meningiomas from other dural-based lesions like lymphoma is essential for appropriate patient management.
Implications:
- Careful evaluation of neuroimaging is necessary to differentiate meningiomas from mimickers.
- Non-Hodgkin lymphoma can present as a dural mass mimicking meningioma.
- Accurate diagnosis through comprehensive assessment is vital for effective treatment of CNS pathologies.
