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[Wound infection following appendectomy. Metronidazole vs ornidazole as single-dose prophylaxis in non-perforated
A Barth1, P Kuhn, W Bertschmann
1Chirurgische Klinik, Bürgerspital Solothurn.
Schweizerische Medizinische Wochenschrift
|October 1, 1988
Abstract:
In an open prospective randomized study, the postoperative wound infection rate following removal of an unperforated appendix was evaluated in 187 patients who received either metronidazole (1 g suppositories) or ornidazole (500 mg iv or 500 mg suppositories) in a single dose preoperatively. The overall postoperative infection rate was 2.1%. Metronidazole and ornidazole suppositories are a cheap method of preventing postoperative infection in cases of unperforated appendix.