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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
Assignment of human gene encoding testis-specific lactate dehydrogenase C to chromosome 11, region p14.3-p15.5
Somatic Cell and Molecular Genetics
|September 1, 1988
Abstract:
The human gene coding for lactate dehydrogenase C (LDHC), a testis-specific isozyme, has been assigned to a refined region of chromosome 11, p14.3-p15.5, in which the lactate dehydrogenase A gene (LDHA) also resides, by using somatic cell hybrids and in situ chromosome hybridization. This assignment clearly indicates the close physical proximity of the LDHC and LDHA genes and supports the evolutionary closeness of these two isozymes.
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