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Updated: Jan 3, 2026

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Novel Therapies for Treatment of Food Allergy
Sultan Albuhairi1, Rima Rachid2
1Department of Pediatrics, College of Medicine, Majmaah University, PO Box 66, Majmaah 11952, Saudi Arabia.
Abstract:
Food allergy prevalence has increased over the past 2 decades and is estimated to affect 8% of children and 4% to 10% of adults. There is an unmet need to evaluate new therapeutic modalities that may decrease the risk of food-induced anaphylaxis and improve patients' quality of life. Oral, epicutaneous, and sublingual food immunotherapies have different safety and efficacy profiles, and their long-term outcome and applicability are unclear. Food allergy trials are currently evaluating different biologics (given as monotherapy or adjunct to immunotherapy), modified food proteins, DNA vaccines, and fecal microbiota transplantation.
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